water pollution with medicinal preparations, basic medications-pollutants, methods of water cleaning from medicines


Purpose. The paper aimed at analyzing the presence of residual quantities of medicinal preparations in the water of Ukraine and the world. Based on the world and own experience to propose methods for waters cleaning from medicines. Methodology. The research was carried out on the basis of analysis of scientific sources and reporting data on the availability of medicines in the water of Ukraine, European countries, the USA (1999-2017). Findings. Analyzed sources inform that the main environmental threat of a global scale is the presence of medicines in drinking water. The treatment facilities are not suitable for the detection and decomposition of medicinal preparations. The fight against these substances is not envisaged all over the world. The authors present the results of a comprehensive review of issues related to the determination of the medicines availability in various waters, their concentrations and the most dangerous medicinal preparations - toxicants. Medications can be accumulated not only in the body of humans and animals, but also in marine and river fish, etc. The impact of even trace amounts of certain medicines (drugs, hormones) can have a negative effect on the health of more vulnerable segments of population, such as children. It was found that the main culprit of hormonal water pollution is agriculture, namely animal husbandry. Originality. The paper summarizes available and presents new methods and technologies for water cleaning, such as: electrochemical, membrane, adsorption based on activated carbon, ultrasonic treatment in the presence of catalysts, treatment of water with enzymes and persulfates. As the second way to reduce the number of medicines in the water, it is proposed to produce environmentally friendly medicines. Practical value. Water problems are the main ones all over the world and in Ukraine as well. It is necessary to provide the additional financing to solve the problem of water cleaning from medicines not on a residual principle, but considering that water is the basis of life on the Earth, and in general the health and life of mankind depends on the quality of water.

Author Biographies

L. F. Dolina, Dnipropetrovsk National University of Railway Transport named after Academician V. Lazaryan

Dep. «Hydraulics and Water Supply», Dnipropetrovsk National University of Railway Transport named after
Academician V. Lazaryan, Lazaryan St., 2, Dnipro, Ukraine, 49010,
tel. +38 (056) 273 15 09,
Email: water.supply.treatment@gmail.com

O. P. Savina, Dnipropetrovsk National University of Railway Transport named after Academician V. Lazaryan

Dep. «Hydraulics and Water Supply», Dnipropetrovsk National University of Railway Transport named after 
Academician V. Lazaryan, Lazaryan St., 2, Dnipro, Ukraine, 49010, 
tel. +38 (056) 273 15 09, 
Email: savina.o.p@gmail.com


Andryushchenko, Y. (2017). Lekarstva travyat pityevuyu vodu. Dnepr vecherniy, 49(13211), 23. Retrived from http://dv-gazeta.info/vechyorka/zdorovje/lekarstva-travyat-pitevuyu-vodu.htm (in Russian)

Bakterii obzavelis immunitetom (2014). Sankt-Peterburgskie Vedomosti, October 16. Retrieved from: https://spbvedomosti.ru/news/obshchestvo/bakterii_obzavelis_immunitetom/ (in Russian)

Barenboym, G. M., & CHiganova, M. A. (2015). Zagryazneniye prirodnykh vod lekarstvami. Moscow: Nauka. (in Russian)

Belousov, Y. B., Moiseev, V. S., & Lepakhin, V. K. (1997). Klinicheskaya farmakologiya i farmakoterapiya. Moscow: Universum Pablishing. (in Russian)

Korzh, Y. A., Klimenko, N. A., Smolin, S. K., & Reshetnyak, L. R. (2016). Biosorbtsiya prokaina na biologicheski aktivnom ugle. Journal of Water Chemistry and Technology, 38(5), 519-530. (in Russian)

Voda v butylkakh opasnee vodoprovodnoy (n.d.). Retrived from https://www.epochtimes.ru/content/view/69576/7/ (in Russian)

Dolina, L. F. (2003). Novye metody i oborudovaniya dlya obezzarazhivaniya stochnykh i prirodnykh vod: monografiya. Dnepropetrovsk: Kontinent. (in Russian)

Dolina, L. F. (2001) Reaktory dlya ochistki stochnykh vod: uchebebnoe posobie. Dnepropetrovsk: Standart. (in Russian)

Korzh, Y. A., Smolin, S. K., & Klimenko, N. A. (2016). Kinetika adsorbtsii farmatsevticheskikh veshchestv iz vodnykh rastvorov na aktivnykh uglyakh. Journal of Water Chemistry and Technology, 38( 4), 342-353. (in Russian)

Kofman, V. Y. (2013). New advanced oxidation technologies of water and wastewater treatment (part 2) (foreign publications review). Water Supply and Sanitary Technique, 11, 70-77. (in Russian)

Lekarstva i lekarstvennaya bolezn (n.d.). Retrived from http://www.medn.ru/statyi/lechenie-solyu-skipidarom-kerosinom/lekarstva-i-lekarstvennaya-bolezn.html (in Russian)

Livshits, V. (n.d.). Lekarstva kak ekologicheskaya problema. Retrived from http://proza.ru/2013/02/27/1830 (in Russian)

Danilov-Danilyan, V. I., Poroykov, V. V., Chiganova, M. A., Kozlov, M. N., Filimonov, D. A., & Barenboym, G. M. (2013). Otsenka biologicheskoy opasnosti organicheskikh ksenobiotikov v istochnikakh vodosnabzheniya. Water Supply and Sanitary Technique, 10, 17-24. (in Russian)

Farmatsevticheskie sredstva v pitevoy vode. (n.d.). Retrived from http://www.who.int/water_sanitation_health/emerging/info_sheet_pharmaceuticals/ru/ (in Russian)

Shpakov, A. (1999). Antibiotiki i steroidy otravlyayut stochnye vody: Smert iz kanalizatsii. Komersant, 110. Retrived from https://www.kommersant.ru/doc/220792 (in Russian)

Al-Khazrajy, O. S. A., Bergström, E., & Boxall, A. B. A. (2017). Factors affecting the dissipation of pharmaceuticals in freshwater sediments. Environmental Toxicology and Chemistry, 37(3), 829-838. doi: 10.1002/etc.4015 (in English)

Boxall, A. B. A. (2004). The environmental side effects of medication. EMBO Reports, 5(12), 1110-1116. doi: 10.1038/sj.embor.7400307 (in English)

Domercq, P., Praetorius, A., & Boxall, A. B. A. (2018). Emission and fate modelling framework for engineered nanoparticles in urban aquatic systems at high spatial and temporal resolution. Environmental Science: Nano, 5(2), 533-543. doi: 10.1039/c7en00846e (in English)

Fent, K., Weston, A., & Caminada, D. (2005). Ecotoxicology of human pharmaceuticals. Aquatic Toxicology, 76(2), 122-159. doi: 10.1016/j.aquatox.2005.09.009 (in English)

Williams, R. (Ed.). (2005). Human Pharmaceuticals: Assessing the impacts on aquatic ecosystems. Pensacola: SETAC.

Desbiolles, F., Malleret, L., Tiliacos, C., Wong-Wah-Chung, P., & Laffont-Schwob, I. (2018). Occurrence and ecotoxicological assessment of pharmaceuticals: Is there a risk for the Mediterranean aquatic environment? Science of the Total Environment, 639, 1334-1348. doi: 10.1016/j.scitotenv.2018.04.351 (in English)

Probe: Pharmaceuticals In Drinking Water (n.d.). Retrived from https://www.cbsnews.com/news/probe-pharmaceuticals-in-drinking-water/ (in English)

Sumpter, J. P. (2010). Pharmaceuticals in the Environment: Moving from a Problem to a Solution. In Kummerer, K., & Hempel, M. (Eds.), Green and Sustainable Pharmac (pp.11-22). Berlin: Springer-Verlag. (in English)

Dolina, L. F., Mashykhina, P. B., Karpo, A. A., & Mishchenko, A. A. (2017). Waters reality in Ukraine worldwide. Science and Transport Progress, 5(71), 7-18. doi: 10.15802/stp2017/113695 (in English)



How to Cite

Dolina, L. F., & Savina, O. P. (2018). WATER CLEANING FROM RESIDUES OF MEDICINAL PREPARATIONS. Science and Transport Progress, (3(75), 36–51. https://doi.org/10.15802/stp2018/134675